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Diapathy
Natural prevention for neuropathic complication, (retinal, renal, cardiac, vascular) due to diabetes
Active ingredients: Pueraria lobate root extract, Vitis vinifera extract, Red Korean ginseng, Piper nigrum extract; Vanadyl sulphate; Alpha Lipoic Acid.
Radix Pueraria lobata (RP) is the dried root of Pueraria lobate (Ohwi), which is used traditionally to treat diarrhea, muscle stiffness, thirst, and diabetes in East Asia, and recently was made commercially available as a western dietary supplement. It is a rich source of isoflavone glucosides and puerarin is the most abundant constituent of RP. Previous studies have reported that chronic administration of RP extract improved glucose tolerance and decreased fasting plasma glucose levels and that puerarin supplementation reduced body weight gain and lipid levels in liver and serum of high-fat-diet (HFD) subjects.
Ginseng & Alpha lipoic acid : Combating Diabetic Neuropathy
Ginseng is well known for its complex activity profile that includes antioxidant, anti-inflammatory, anti-apoptotic, and immune- stimulatory properties, stabilizing and balancing the entire physiology.
Alpha lipoic acid (LA) has been used in Germany for over 30 years for the treatment of diabetes- induced neuropathy. The overall conclusions from controlled clinical studies show reduction of the main symptoms of diabetes induced polyneuropathy, accompanied by an improvement in neuropathic deficits and cardiac autonomic neuropathy. Also, preliminary data suggest an improvement in motor and sensory function in lower limbs.
Vanadium Compounds: Mimicking Insulin to Treat Diabetes
Vanadium (including vanadyl and vanadate) has been shown to reduce blood glucose level by stimulating glycogenesis and by inhibiting glucose formation via hepatic gluconeogenesis and glycogenolysis. It has been found that vanadium and vanadium compounds exhibit an insulin-like activity by imitating insulin actions via insulin-receptor tyrosine kinase activation and kinase phosphorylation cascade pathways. Vanadyl sulfate has been suggested in scientific research reports as a therapeutic agent for the treatment of type 1 diabetes.
